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The wonders of a 400 MHz HTS magnet NMR system, how it works and our results at Amgen - Livestream

Maria Victoria Silva Elipe

The discovery of new ceramic materials containing Ba-La-Cu oxides in 1986 exhibiting superconductive properties at high temperatures (35 K or higher), opened a new world of opportunities for NMRs and MRIs to move away from liquid cryogens, recognized with the Nobel Prize in Physics in 1987. A prototype 400 MHz high temperature superconducting (HTS) power-driven magnet NMR spectrometer was installed at Amgen’s chemistry laboratory to be tested for a variety of applications, structure analysis, reaction monitoring, and CASE-3D studies with RDCs. The HTS “cryofree” magnet does not required liquid cryogens refills and has a smaller footprint than a comparable low temperature superconducting (LTS) magnet, with stability as the unknown factor of this technology. Our evaluation of its performance was successful.

Speaker: Maria Victoria Silva Elipe, Amgen

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Friday, 06/21/24

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Free

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California Section American Chemical Society


, CA