Signal (re)processing: How disease states shape signal transduction in CD8+ T cellsPersistent antigen signaling is known to drive CD8+ T cell exhaustion (TEX) in cancer and chronic infection, but which downstream kinase cascades control this process are unknown. We found that activation of protein kinase C (PKC) triggers degradation of PKC theta while sparing PKC eta, leading to terminal TEX cells. In chronic ...
In this talk, Brent Pease will discuss how darkness during the day affected wildlife and highlight the power of the public in large-scale research. Dr. Pease played a key role in the Eclipse Soundscapes project as a facilitator, organizing and engaging almost 100 volunteers to participate as Data Collectors during ...
