Complex glycans are directly involved in essential life processes, but it is challenging to precisely assemble them in sufficient quantities with high homogeneity. One major hurdle is that the stereoselectivity in glycosylation often varies with substrates, thus it is difficult to develop an exquisitely selective glycosylation method that is also ...
Thermodynamics is among the most successful frameworks in the physical sciences because it explains how and why systems at or near equilibrium undergo dramatic transformations. Yet many living and active systems are sustained far from equilibrium, where the usual thermodynamic framework need not apply. In this talk, I will provide ...
Sulfur and selenium occupy a unique position at the interface of inorganic chemistry, redox chemistry, and biology, where changes in oxidation state, speciation, and metal coordination can profoundly alter reactivity. Understanding the fundamental chemistry of reactive S and Se species therefore provides a framework for connecting molecular structure and bonding ...
