Engineering Skin Bacteria for Needle-Free Topical VaccinationThe ubiquitous skin colonist Staphylococcus epidermidis elicits a CD8+ T cell response pre-emptively, in the absence of infection, but the scope and purpose of this program remain unclear. Here, we show that this colonist also induces a potent, durable, and specific antibody response. Colonizing mice with S. epidermidis engineered to ...