Protein structure and dynamics using X-ray free-electron lasers - CANCELED

X-ray crystallography has tremendous impact on biology, having yielded the structures of thousands of proteins and given detailed insight into their working mechanisms. The requirement for macroscopic crystals, which can be difficult to obtain, as well as the often severe radiation damage caused by the ionizing X-rays during data acquisition - in particular when using small crystals - has been relieved with the advent of X-ray free-electron lasers (XFELs). With their highly brilliant short X-ray pulses XFELs enable room temperature measurements, allowing to perform time-resolved experiments at atomic resolution at the chemical timescale of femtoseconds. It is now ten years since the Linac Coherent Light Source opened its doors to users. Time to reflect what has been achieved and to think about future challenges.

Speaker: Ilme Schlichting, Max Planck Institute for Medical Research

Editor's Note: This seminar has been canceled.