The second dimension of the genetic codeDNA stores genetic information in the sequence of the four canonical bases dA, dC, dG, and T and, in addition, carries epigenetic information encoded by the four modified cytidine bases: 5-methylcytidine (mdC), 5-hydroxymethylcytidine (hmdC), 5-formylcytidine (fdC), and 5-carboxycytidine (cadC), with 5-hydroxymethyluridine (hmdU) potentially playing a role as well. These additional ...