Natural product (NP) total synthesis involves experimental discovery and decision-making at every stage: why this route and not another? Why this intermediate and not its close analog? Why this NP, optimized for the producer organism’s survival in its ecological niche, and not a close analog, optimized for therapeutic use? The ...
Atmospheric N2 is a cheap, abundant resource with great potential for energy storage and chemical synthesis, but it is difficult to convert it into other compounds (“fixing” nitrogen). This seminar will describe some challenges and opportunities of nitrogen fixation, as well as my students’ discoveries of how to break the ...
